Gibson SOLA

closes the loop

AI predicts and designs faster than ever. But every model-driven experiment still needs physical DNA. Gibson SOLA brings the build step in-house so designs can become expression-ready DNA, experiments can generate new data, and the next learning cycle can begin.

A CHANGING PARADIGM

Prediction got faster. The physical build step did not.

Agentic workflows have accelerated the pace and scale of experimentation. The connection from AI prediction to physical testing is paramount and traditional methods are falling behind. Getting predicted sequences into the lab as testable DNA is now the bottleneck.

Fast predictions, Fast experiments,

One slow handoff.

Outsourced DNA slows down experimental progress and limits learning rate.

MODEL

LAB

PREDICT

More hypotheses

AI models generate and refine candidate sequences at a pace that expands the need for data generation.

EVALUATE

More experiments

Autonomous wet labs can test more designs, creating demand for more frequent, data-rich build-test cycles.

BUILD

DNA is the constraint

Every experiment still depends on physical DNA. If DNA availability lags behind design, the learning loop waits.

THE BOTTLENECK

When DNA is outsourced, the loop stops at Build

An external order-and-wait cycle separates a model’s prediction from the experiment that could validate it. During that wait, teams run fewer iterations and new data arrives later, slowing down your learning rate.

The model hypothesizes

Candidate sequences are generated for the next experiment

DNA enters a queue

Ordering and delivery add an external wait before the lab can start

Experiments are delayed

Lab capacity and resources wait for physical constructs

The learning rate slows

Iteration slows down, data is lagging, and model maturity is delayed

THE GIBSON SOLA SOLUTION

Eliminate the wait. Close the loop. Accelerate your model maturation.

The Gibson SOLA platform is designed to integrate into your autonomous lab, from software to automation, powered by made-to-stock reagents. Unlock <36 hour, fully autonomous design to data cycles. Your AI predicts, Gibson SOLA optimizes & builds, and your pipeline turns predictions into data - and data into better predictions.

Fully autonomous. Design to data in <36 hours.

THE IMPACT

More data. Faster.

Shorter iteration cycles and lower cost per data point enable you to test more sequences, challenge more assumptions, and improve your model faster.

SPEED

More Learning Within Your Timeline

COST

More Data Within Your Budget

Fuel your AI with data. Advance your model faster.

About Telesis Bio

Telesis Bio enables researchers to eliminate outsourcing delays and boost productivity by enabling rapid, on-site synthesis of high-fidelity DNA and mRNA with its Gibson SOLA® platform. Designed to integrate with standard lab automation, Gibson SOLA gives scientists full control over build timelines and IP. From antibodies to cell therapies, innovators across biotech and pharma use Telesis Bio to accelerate development in synthetic biology and therapeutic discovery.

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