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Category: Technology


June 9, 2023

How to Reduce Lead Synthesis Bottlenecks in Antibody Discovery

What is Therapeutic Antibody Discovery and Why is it Important? Antibody therapeutics have tremendous research and clinical value having the potential to combat different diseases such as cancers, HIV, autoimmune, hereditary, and more. The technologies used to discover these antibody-based…


March 2, 2023

In our DNA: Pavel Ryzhov, Field Application Scientist

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Pavel Ryzhov, Field Application Scientist Came aboard: April 2022 What do you do at Telesis Bio? I work with…


February 22, 2023

Synthetic Biology: Broadening the Horizons of Antibody Discovery

Since Köhler and Milstein first succeeded in fusing myeloma cell lines with B cells to create hybridomas in 1975,1 antibodies have become well-established therapeutics. With advantages relative to selectivity, effector function, and bioavailability over small molecule drugs, antibody therapeutics are…


January 31, 2023

Removing bottlenecks in discovery workflows with synthetic biology solutions

Cellular therapy research is booming with applications in cancer and further innovations on the horizon for infectious, autoimmune, and chronic inflammatory diseases. The progression in understanding the tumor microenvironment and how the immune cells infiltrate and kill tumor cells has…


December 20, 2022

How product design was integral to developing a next-generation automated synthetic biology workstation

Laurence Warden, Senior Vice President, Engineering and Instrumentation, led his team to develop the BioXp® 9600 system – a high-throughput benchtop platform for synthetic biology workflows designed to empower scientists to accelerate the discovery of new vaccines and biologics. Read…


September 19, 2022

Harnessing the Power of Synthetic Biology

Introducing the Next Generation Automated Synthetic Biology Workstation Telesis Bio recently announced the commercial release of the BioXp® 9600 system – a fully automated, high-throughput benchtop platform for synthetic biology workflows designed to empower scientists to accelerate discovery of new…


September 14, 2022

In our DNA: Silvio Cenzi, Senior Manager, Field Service Field Support

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Silvio Cenzi, Senior Manager, Field Service Field Support Came aboard: January 10, 2022 What do you do at Telesis…


September 7, 2022

How synthetic biology is transforming agriculture

Ben Chiarelli, Founder and CEO of Cellibre, a company revolutionizing agricultural manufacturing, discussed the company’s goal of shortening their complex design-build-test process to produce globally significant products at scale. Ben also shared how the partnership with Telesis Bio empowered their…


August 24, 2022

Optimizing production workflows with the BioXp® system

We caught up with Jason Lehmann, Senior Product Marketing Manager at Telesis Bio, as he shares how our synthetic biology workstation, the BioXp® system, can accelerate your time to results by optimizing production workflows and overcoming synthesis bottlenecks. How do…


August 17, 2022

In our DNA: Ken Williams, Bioinformatics Scientist Lead

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Ken Williams, Bioinformatics Scientist Lead Came aboard: February 2020 What do you do at Telesis Bio? I develop the…


June 22, 2022

In our DNA: Sydney Kerr, Senior Research Associate

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Sydney Kerr, Senior Research Associate Came aboard: January 2021 What do you do at Telesis Bio? I work on…


May 16, 2022

In our DNA: Michelle Vargas, Scientist

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Michelle Vargas, Scientist Came aboard: March 2021 What do you do at Telesis Bio? I work on the Research…


April 21, 2022

Event Recap: Built with Biology (formerly SynBioBeta) Hosts the Global Synthetic Biology Conference

Built with Biology (Formerly SynBioBeta) hosted its global synthetic biology conference in Oakland, CA last week. The conference brought together synthetic biology’s leading community of innovators, investors, and thought leaders to collaborate in solving our world’s biggest problems through biology.…


March 30, 2022

In our DNA: John Gill, Senior Director of Research and Development

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: John Gill, Senior Director of Research and Development Came aboard: April 2020 What do you do at Telesis Bio?…


February 16, 2022

In our DNA: Elijah Grote, Software Engineer

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Elijah Grote, Software Engineer Came aboard: November 2020. What do you do at Telesis Bio? I add features and…


February 1, 2022

Todd Nelson, Telesis Bio, CEO, NBC 7 San Diego Interview

On Monday, January 24th, NBC 7 San Diego reporter Madison Weil interviewed Telesis Bio’s CEO, Todd Nelson, to discuss our recent early access collaboration and licensing agreement with Pfizer. Under this agreement, Pfizer gains early access to Telesis Bio’s proprietary…


January 26, 2022

In our DNA: Yanming Gong, Director of Synthesis

We’re continuing our blog series, looking at the DNA of Telesis Bio — our incredible employees and their stories. Team member: Yanming Gong, Director of Synthesis Came aboard: September 2021. What do you do at Telesis Bio? I work in…


December 21, 2021

Dan Gibson, CTO named Industry Disruptor by Newsweek Magazine

We’re proud of Telesis Bio’s Co-Founder and CTO, Dan Gibson, for being featured in this year’s Newsweek Magazine’s America’s Greatest Disruptor list. With his team of scientists at Telesis Bio, Dan Gibson is focused on creating a new paradigm for…


November 17, 2021

Empowering Scientists to Make Breakthrough Discoveries to Address Humanity’s Greatest Challenges

Telesis Bio’s mission is to drive innovation and apply breakthroughs in automation solutions for DNA, mRNA, and protein synthesis. These tools enable scientists to “write” biology for the betterment of the world, creating sustainable healthcare and technology solutions for humanity’s…


October 28, 2021

How the BioXp® System Can Make a Difference in Your Research

It’s been one year since we launched the BioXp® 3250 system — our fully automated biology for gene synthesis, cloning, mRNA synthesis, variant DNA libraries, and more — and we’re excited to see how much progress researchers have made with…


October 4, 2021

Bringing Bright Minds Together for the Discovery on Target Conference

The Discovery on Target 2021 conference took place Sept 28-30 in Boston, bringing together several experts from across the US and globally to foster collaboration and share the latest advances in addressing key challenges in drug discovery. At this year’s…


September 29, 2021

How Synthetic Biology Has Shaped the COVID-19 Response

Across the life sciences, researchers have contributed significantly to the response to COVID-19 — elucidating the pathogen, tracking the progression and consequences of infection, and uncovering many of the biological mechanisms associated with patients who display symptoms for months or…


August 25, 2021

A Tour of Key Milestones in Synthetic Biology

Synthetic biology has become so important and widely used that it’s easy to forget how young the field is. Much of the innovation that we rely on today took place in just the last two decades. Telesis Bio was originally…


August 18, 2021

In our DNA: Gary Mills, Director of Software Engineering

Team member: Gary Mills, Director of Software Engineering What do you do at Telesis Bio? I work on the BioXp® system, both the 3200 and 3250. My team works on the software and scripting that run the protocols for the…


August 11, 2021

With mRNA Capping Technology, We’re Improving Synthesis Yields

If you’re working with synthetic mRNA, we have exciting news to share. In addition to releasing a new workflow earlier this year that makes it possible to synthesize mRNA form pooled oligos in a single overnight run on our BioXp®…


August 4, 2021

Unlock the potential of BioXp® automation solutions for bio-fuel production

Our BioXp® automated end-to-end benchtop system has been used by scientists in many different focus areas to advance breakthroughs in protein engineering. We are delighted to share a great example of utilizing BioXp gene and clone workflows to build recombinant…


July 28, 2021

Happy RNA Day!

RNA Day is on Sunday, August 1st this year, and we welcome the international celebration of one of the most versatile biomolecules we have seen come to life. We have seen RNA play a key role in addressing the COVID-19…


June 30, 2021

Telesis Bio and MBC Biolabs partner for discovery and automation of synthetic biology applications

We’re thrilled to announce the partnership with MBC Biolabs, a premier biotech incubator in the Bay Area. Under the terms of the collaboration, MBC Biolabs will leverage Telesis Bio’s BioXp® system to empower entrepreneurs in life sciences research with the…


June 23, 2021

Case study: How Cellibre transformed enzyme engineering with Telesis Bio

In San Diego, scientists at ag biotech startup Cellibre are looking to replace traditional agriculture for producing high-value ingredients. One of their first targets is the highly valuable cannabinoid market, which they believe can be disrupted by producing natural, high-quality,…


May 26, 2021

Scientists use automated DNA synthesis to identify response to antimicrobial threats

Scientists use automated DNA synthesis to identify regulatory mechanism in E. coli response to antimicrobial threats. Bacterial resistance to antibiotics is a looming public health crisis, and scientists continue to investigate how to better characterize the molecular mechanisms underpinning this…


April 14, 2021

Telesis Bio partners with researchers to discover a new way to control citrus greening disease

The bacterial scourge of the citrus greening disease has affected citrus production worldwide, causing tree decline and a serious threat to Florida’s citrus industry. Citrus greening disease, or Huanglongbing (HLB), is caused by Candidotus liberibacter (CLass) and is spread by…


March 24, 2021

For HIV vaccine study, scientists build pooled variant library using automated DNA synthesis

The quest for an effective vaccine against HIV has spanned decades. While the vaccine itself remains elusive, researchers are making important strides in figuring out how best to design and develop it. Recently, scientists from Duke University and NIH’s Vaccine…


February 10, 2021

Scientists use Telesis Bio technology to discover fever-protective element in malaria parasite

Scientists have made a new discovery that could eventually lead to more effective treatment for malaria. In a series of experiments that included using the BioXp® system, they determined that a key phospholipid and a related protein confer protection against…


January 20, 2021

Targeted mutagenesis could streamline antibody engineering

Monoclonal antibodies represent an important class of therapies for an ever-increasing number of diseases, infections, and health conditions. That’s why scientists around the world are working to improve the processes required to engineer new antibody candidates for therapeutic use. The…


January 13, 2021

Ready-made SARS-CoV-2 genomes from Telesis Bio power development of vaccines, therapies, and diagnostics

Since the start of the COVID-19 pandemic, the Telesis Bio team has been working hard to ensure that our customers have access to the tools they need to help in the fight against this public health scourge. We currently offer…


December 23, 2020

T cell engineering: How the BioXp® system boosts productivity and decreases discovery time

At a recent Oxford Global NextGen Omics UK congress, our own Kirsty Maclean gave a presentation about how the BioXp® system is powering advances in cell engineering. While she started with a high-level view of how synthetic biology applies to…


December 16, 2020

A vaccine printer at your local drugstore? We are making it happen

You probably know Telesis Bio as the developer of the world’s first and only automated benchtop solution for generating gene fragments, clones, and libraries. While we’re incredibly proud of what we’ve accomplished so far, our mission goes well beyond streamlining…


December 9, 2020

BioXp® system chosen as one of the year’s best innovations by The Scientist

There’s celebrating in the halls — and virtual halls — of Telesis Bio. We are truly honored that our new BioXp® 3250 system was selected as one of the year’s best innovations by The Scientist. This is a very prestigious…


November 24, 2020

In pandemics, rapid DNA synthesis accelerates vaccine development

Back in 2013, I played a small role in response to what then seemed like the next potential pandemic — an outbreak of H7N9, an avian influenza virus. At the time, I was working with Novartis scientists, and we were…


November 11, 2020

Scientists develop nanobody treatments with the BioXp® system

In the age of COVID-19, there has been a ton of scientific interest in nanobodies, or single-domain antibodies that can be used for finely targeted viral vaccines. It’s also been a hot topic among users of our BioXp® system —…


November 4, 2020

Rapid discovery + development of a monoclonal antibody to combat SARS-CoV-2

Without question, the global outbreak of the novel coronavirus 2019 (SARS-CoV-2) that causes COVID-19 has dominated scientific discussion and has been fodder for a wealth of publications as the world urgently races for a better understanding of the mechanism of…


October 28, 2020

Telesis Bio celebrates Breast Cancer Awareness Month with great science

Breast cancer is now recognized as the most common malignancy worldwide among women, irrespective of age. Today’s standard of care and breast cancer management relies heavily on chemotherapy, hormone therapy, and targeted therapy. However, there is still much to be…


October 21, 2020

Highlights from the SynBioBeta 2020 Conference

The Telesis Bio team really enjoyed attending this year’s virtual Global Synthetic Biology Conference hosted by SynBioBeta. If you missed the event, we’ve got you covered — here’s our take on highlights from the meeting. BioXp® system in the spotlight…


September 30, 2020

Accelerating therapeutic discoveries for lymphoma

The treatment landscape for lymphoma – especially aggressive B-cell lymphomas — has been transformed by adoptive cellular immunotherapy with chimeric antigen receptor (CAR) T cells. Clinical trials with a focus on anti-CD19 CAR-T cell therapy have shown efficacy and long-term…


August 26, 2020

Meet the BioXp® 3250 system, our new automated synthetic biology workstation

Please join us in welcoming the newest member of the Telesis Bio family. Like its BioXp® 3200 predecessor, the BioXp® 3250 system is a fully automated, benchtop platform for synthetic biology workflows — but this one reduces the timelines for…